Oryx Pharmaceuticals and Novartis Pharmaceuticals Enter Into Agreement For Central Nervous Sytem Products

Mississauga, Ontario (September 3, 2002) — Oryx Pharmaceuticals Inc. is pleased to announce the acquisition of the Canadian rights to Anafranil® and Restoril® from Novartis Pharmaceuticals Canada Inc. Anafranil (clomipramine) is indicated for the treatment of depression and for the treatment of obsessions and compulsions associated with obsessive compulsive disease. Restoril (temazepam) is indicated for the symptomatic relief of transient and short-term insomnia.

"We are pleased to be acquiring these important products as they enhance our portfolio of products for diseases of the central nervous system"said Doug Reynolds, President of Oryx. Oryx recently launched FXT 40® (fluoxetine), which is the only 40 mg capsule of fluoxetine available for Canada and introduced Trileptal® (oxcarbazepine) for the treatment of epilepsy in a promotion agreement with Novartis.

About Oryx

Oryx Pharmaceuticals Inc is a new and dynamic Canadian specialty pharmaceutical company with offices in Mississauga, Ontario. Its mission is to serve the needs of Canadian health care professionals and patients through the licensing and commercialisation of unique pharmaceutical products. Oryx is focused in the therapeutic areas of CNS, cardiovascular disease and oncology. For further information, please consult http://www.oryxpharma.com.

About Novartis

Novartis AG (NYSE: NVS) is a world leader in healthcare with core businesses in pharmaceuticals, consumer health, generics, eye-care, and animal health. In 2001, the Group's businesses achieved sales of CHF 32.0 billion (USD 19.1 billion) and a net income of CHF 7.0 billion (USD 4.2 billion). The Group invested approximately CHF 4.2 billion (USD 2.5 billion) in R&D. Headquartered in Basel, Switzerland, Novartis Group companies employ about 72 600 people and operate in over 140 countries around the world. For further information please consult www.novartis.com.


Primary Contact Information:

Doug Reynolds
President
Oryx Pharmaceuticals Inc.
Tel. (866) 260-6291 (toll free) Ext. 6773
dougr@oryxpharma.ca

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